Table 1 Values of the parameter model

s

production of constant hepatocyte

1 cell day⁻¹ mL⁻¹

\(d_{\mathrm{T}}\)

death rate of hepatocyte

0.01–9 × 10⁻⁴ day⁻¹

β

rate of infectivity

1 × 10⁻¹⁰–6.6 × 10⁻⁸ mL virions⁻¹ day⁻¹

δ

infected hepatocytes killing rate

0.06–0.25 day⁻¹

ρ

rate of recovery

0 day⁻¹

v

virus production

1.4–164 virions cell⁻¹ day⁻¹

c

virus clearance

0.18–1 day⁻¹

η

effect of therapy in blocking infection

0.2–0.5

ε

effect of drug in blocking new virus production

0.99934–1