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Blow-up and delay for a parabolic–elliptic Keller–Segel system with a source term
Boundary Value Problems volume 2018, Article number: 95 (2018)
Abstract
In this paper, we are concerned with the parabolic–elliptic Keller–Segel system with a positive source term in a bounded domain in \({\mathbb{R}}^{N}\) (\(N=2,3\)), under homogeneous Dirichlet boundary condition, with time-dependent coefficients. Lower bounds for the blow-up time if the solutions blow up in finite time are derived under appropriate assumptions on data. Moreover, the exponential decay of the associated energies is also studied.
1 Introduction
Let us consider the following parabolic–elliptic Keller–Segel system:
where Ω is a bounded convex domain in \({\mathbb{R}}^{N}\) (\(N=2,3\)) with smooth boundary, \(k_{i}(t)\) (\(i=1,2,3\)) are positive and regular functions of t, \(u_{0}(x)\) is a nonnegative function in Ω. Moreover, in the first equation, we assume that \(f(u)\) is a nonnegative function and m is a positive constant.
The classical Keller–Segel system
was originally introduced in 1970 by Keller and Segel in [11], and it represents a fundamental model, which has great interest in biology, where Ω, denoting the capacity, is an open domain in \({\mathbb{R}}^{N}\) (\(N\geq1\)), ∇ is the gradient operator , \(U(x,t)\) denotes the cell density, and \(V(x,t)\) represents the chemo-attractant. \(\mu>0\) is the amoeboid motility, \(\chi>0\) is the chemotactic sensitivity, \(D>0\) is the diffusion rate of cAMP, \(g>0\) is the rate of cAMP secretion per unit density of amoebae, \(k>0\) is the rate of degradation of cAMP in environment. The cross-diffusion term in the first equation reflects the assumption that individual cells partially adapt their motion so as to migrate toward increasing chemo-attractant.
In the last three decades, much attention has been devoted to studying the type of model (1.2) and its variations. See, for example, for system (1.2) with \(\Omega={\mathbb{R}}^{N}\), \(\mu=\chi=D=1\), \(k=0\). Kozono, Sugiyama, and Takada in [12] considered the problem whether there exists a finite-time self-similar solution of the backward type for the case of \(N\geq2\), and Sugiyama and Yahagi in [22] investigated the uniqueness and continuity of weak solutions with respect to the initial data for the Keller–Segel system of degenerate type. For more contribution along this line, we can see [3–6, 19–21], and the references therein.
In view of the biologically meaningful question whether or not cell populations spontaneously form aggregates, some studies focused on the issue whether solutions remain bounded or blow up (see [7–10, 16–18, 23, 26]).
Because practical experiences show how the specific parameters modeling chemotaxis phenomena are a general chemotaxis system, especially those influenced by logistic-type source (see [1, 2, 13–15, 25, 27]). In particular, Marras, Vernier-Piro, and Viglialoro in [15] considered the system
where \(k_{i}(t)\) (\(i=1,2,3,4\)) are positive and regular functions of t, \(f(u)\) is a nonnegative function satisfying \(f(u)\leq c u^{2}\), \(c>0\), and m is a positive constant. They showed that the lower bounds for blow-up time \(t^{*}\) to system (1.3) are obtained in both cases, the Neumann boundary condition (i.e., \(h(t)=0\)) and the Robin boundary condition (i.e., \(h(t)>0\)) for the three-dimensional case and provided \(\frac {2}{3}< m<1\) or for the two-dimensional case and provided \(1\leq m<2\), respectively.
Homogeneous Dirichlet boundary condition for the chemotaxis system is prescribed by the disappearance of cell and chemo-attractant near the boundary.
Our aim in this paper is to investigate the lower bound for the blow-up time and decay criteria of associated energies to the parabolic–elliptic Keller–Segel system (1.1) under Dirichlet boundary conditions for the three-dimensional case and provided \(\frac{2}{3}< m<1\) or for the two-dimensional case and provided \(1\leq m<2\), respectively. Let us point out that although the idea was used before for other problems, the adaptation of the procedure to our problem is not trivial at all. Due to the parabolic–elliptic Keller–Segel system (1.1) under Dirichlet boundary condition, we need more delicate estimates.
From biological point of view, solutions to system (1.1), representing the density and the chemo-attractant, must satisfy
Thus it is reasonable to require throughout that the initial datum \(u_{0}\in C^{0}(\overline{\Omega})\) be nonnegative.
2 Lower bound for blow-up time
In this section, we give lower bounds for blow-up time to system (1.1) in the three-dimensional case and provided \(\frac{2}{3}< m<1\), and in the two-dimensional case and provided \(1\leq m<2\), respectively.
2.1 Lower bound with \(\Omega\subset{\mathbb {R}}^{3}\), \(\frac{2}{3}< m<1\)
In this subsection, in order to obtain a lower bound for the blow-up time \(t^{*}\) of the solution \((u,v)\) to system (1.1) with \(N=3\), we define the following auxiliary function:
with \(\Phi_{0}=\Phi(0)=\alpha(0)\int_{\Omega}u_{0}^{2}\,dx>0\), and α is a suitable time-dependent positive function.
Definition 2.1
We say that \((u,v)\) blows up in Φ-measure at time \(t^{*}\) if
The main result in this subsection is given in the following theorem.
Theorem 2.1
Let \(\Omega\subset{\mathbb {R}}^{3}\) be a bounded convex domain with the origin inside. Suppose that \(f(u)\) is a nonnegative function and satisfies
Moreover, let \((u,v)\) be a classical solution to system (1.1), and \((u,v)\) becomes unbounded in the Φ-measure at time \(t=t^{*}\), with Φ defined in (2.1), then \(t^{*}\) satisfies the lower bound
where
Among that \(\varepsilon_{0}\), \(\varepsilon_{1}\) present positive constants, ν denotes the unit normal vector directed outward on ∂Ω.
Proof
By using Hölder’s inequality and the arithmetic inequality
we obtain
Next, we estimate the term \(\int_{\Omega}u^{3}\,dx\) appearing in (2.7) by means of the following inequality (see Lemma A2 in [17]):
with \(p_{1}=\frac{3}{2\rho_{0}}\), \(p_{2}=\frac{d}{\rho_{0}}+1\), where \(\rho_{0}=\min_{\partial\Omega}x\cdot\nu>0\), \(d=\max_{\overline {\Omega}}|x|\), ν denotes the unit normal vector directed outward on ∂Ω.
From (2.8) and the inequality
we achieve
Inserting this estimate (2.10) into (2.7), we have
where \(\varepsilon_{0}\) is a positive constant.
Then, differentiating \(\Phi(t)\) and using the fact \(u|_{\partial \Omega}=0\), we have
In the forth term (2.12), we use (2.3), (2.8), and (2.9), which leads to
with
Here, we also used Hölder’s inequality and Young’s inequality with \(\varepsilon_{1}>0\).
Inserting (2.11) and (2.13) into (2.12), we obtain
with \(c_{1}=\frac{2\alpha k_{1}k_{3}}{m+1}\).
To simplify the right-hand side of (2.14), we choose appropriate constants \(\varepsilon_{0}\) and \(\varepsilon_{1}\) such that
Hence, we can estimate (2.14) as
where
Now, integrating (2.15) over \((0,t)\), we have
Thus the proof of Theorem 2.1 is completed. □
2.2 Lower bound with \(\Omega\subset{\mathbb {R}}^{2}\), \(1\leq m<2\)
In this subsection, we consider system (1.1) in the case \(\Omega \subset{\mathbb {R}}^{2}\), we have the following main result.
Theorem 2.2
Let \((u,v)\) be a classical solution of system (1.1) in a convex region \(\Omega\subset{\mathbb {R}}^{2}\) with smooth boundary and \(1\leq m<2\). Suppose that \(f(u)\) is a nonnegative function and satisfies (2.3). If \((u,v)\) blows up in the Φ-measure at time \(t^{*}\), with Φ defined in (2.1), then \(t^{*}\) satisfies the lower bound
where
with \(c_{1}\), \(a_{1}\), \(a_{2}\), \(p_{1}\), \(p_{2}\), \(\rho_{0}\), d defined in (2.5). Among that, \(\varepsilon_{1}\), \(\varepsilon_{2}\) present positive constants, ν denotes the unit normal vector directed outward on ∂Ω.
Proof
By using Hölder’s inequality, we obtain
In order to estimate the term \(\int_{\Omega}u^{4}\,dx\), we use the following inequality (see (3.2) and (3.4) in [17]):
with \(\rho_{0}\), d defined in (2.5).
Inserting (2.18) into (2.17), we obtain
Starting from (2.12), if we apply (2.13) and (2.19), we obtain
Now, choosing appropriate constants \(\varepsilon_{1}\) and \(\varepsilon _{2}\) such that
we get
where
Now, integrating (2.21) over \((0,t)\), we have
Thus the proof of Theorem 2.2 is completed. □
3 Exponential decay for the associated energies
In this section, we focus on the exponential decay of the associated energies for system (1.1). We only consider the case when \(\Omega\subset{\mathbb {R}}^{3}\), the case when \(\Omega\subset{\mathbb {R}}^{2}\) being completely similar. In order to state our main result, we need the following condition:
where
and \(\lambda_{1}\) is the first eigenvalue for the boundary value problem as follows:
Remark 3.1
Let us note that upon appropriate choices of \(D_{1}\), \(D_{2}\), \(D_{3}\), \(D_{4}\), and \(\Phi(0)\), one can obtain condition (3.1).
We are now ready to state our main result about the decay of energies for system (1.1).
Theorem 3.2
Assume that \(\Phi(0)>0\), \(2k_{2}>k_{3}\) and condition (3.1) is satisfied. Then the solution decays exponentially to zero in \(L^{2}(\Omega)\).
Proof
Let \((u,v)\) be the unique solution of (1.1), we put
Following the same idea as in the proof of Theorem 2.1, we have
with \(D_{1}\), \(D_{2}\), \(D_{3}\), \(D_{4}\) defined in (3.2).
Inserting the result
we obtain
We claim, by an argument similar to that of Wang, Wang, and Zhou in [24], that
and
By (3.5) and (3.6), there exists a positive constant γ such that
Thus, one has
which yields
This proves that u decays exponentially to zero in \(L^{2}(\Omega)\).
Next, we study the decay behavior of \(\Psi(t)\). Multiplying both sides of the second equation in (1.1) by v and then integrating over Ω, we obtain
Namely,
By Hölder’s inequality and the arithmetic inequality (2.6), we have
Thus,
which together with (3.7) yields
as desired. This completes the proof. □
References
Bellomo, N., Belloquid, A., Tao, Y., Winkler, M.: Toward a mathematical theory of Keller–Segel model of pattern formation in biological tissues. Math. Models Methods Appl. Sci. 25, 1663–1763 (2015)
Cieslak, T., Winkler, M.: Finite-time blow-up in a quasilinear system of chemotaxis. Nonlinearity 21, 1057–1076 (2008)
Fragnelli, G., Mugnai, D.: Carleman estimates for singular parabolic equations with interior degeneracy and non-smooth coefficients. Adv. Nonlinear Anal. 6, 61–84 (2017)
Ghergu, M., Radulescu, V.: A singular Gierer–Meinhardt system with different source terms. Proc. R. Soc. Edinb., Sect. A 138, 1215–1234 (2008)
Ghergu, M., Radulescu, V.: Turing patterns in general reaction–diffusion systems of Brusselator type. Commun. Contemp. Math. 12, 661–679 (2010)
Ghergu, M., Radulescu, V.: Nonlinear PDEs. Mathematical Models in Biology, Chemistry and Population Genetics. Springer Monographs in Mathematics. Springer, Heidelberg (2012)
Herrero, M.A., Velazquez, J.J.L.: A blow-up mechanism for a chemotaxis model. Ann. Sc. Norm. Super. Pisa, Cl. Sci. 24, 633–683 (1997)
Horstmann, D., Wang, G.: Blow-up in a chemotaxis model without symmetry assumptions. Eur. J. Appl. Math. 12, 159–177 (2001)
Horstmann, D., Winkler, M.: Boundedness vs. blow-up in a chemotaxis system. J. Differ. Equ. 215, 52–107 (2005)
Jäger, W., Luckhaus, S.: On explosions of solutions to a system of partial differential equations modelling chemotaxis. Trans. Am. Math. Soc. 329(2), 819–824 (1992)
Keller, E.F., Segal, L.A.: Initiation of slime mold aggregation viewed as an instability. J. Theor. Biol. 26, 399–415 (1970)
Kozono, H., Sugiyama, Y., Takada, R.: Non-existence of backward self-similar solutions of the Keller–Segel system in the scaling invariant class. J. Math. Anal. Appl. 365, 60–66 (2010)
Marras, M., Vernier-Piro, S.: Explicit estimates for blow-up solutions to parabolic systems under nonlocal boundary conditions. C. R. Acad. Bulgare Sci. 67, 459–466 (2014)
Marras, M., Vernier-Piro, S., Viglialoro, G.: Estimates from below of blow-up time in a parabolic system with gradient term. Int. J. Pure Appl. Math. 93, 297–306 (2014)
Marras, M., Vernier-Piro, S., Viglialoro, G.: Blow-up phenomena in chemotaxis systems with a source term. Math. Methods Appl. Sci. 39, 2787–2798 (2016)
Nagai, T.: Blowup of nonradial solutions to parabolic–elliptic systems modeling chemotaxis in two-dimensional domains. J. Inequal. Appl. 6, 37–55 (2001)
Payne, L.E., Philippin, G.A., Vernier-Piro, S.: Blow-up phenomena for a semilinear heat equation with nonlinear boundary condition II. Nonlinear Anal. 73, 971–978 (2010)
Payne, L.E., Song, J.C.: Lower bounds for blow-up in a model of chemotaxis. J. Math. Anal. Appl. 385, 672–676 (2012)
Sugiyama, Y.: Partial regularity and its application to the blow-up asymptotics of parabolic systems modelling chemotaxis with porous medium diffusion. Adv. Stud. Pure Math. 55, 137–160 (2009)
Sugiyama, Y.: On ϵ-regularity theorem and asymptotic behaviors of solutions for Keller–Segel systems. SIAM J. Math. Anal. 41, 1664–1692 (2009)
Sugiyama, Y., Velazquez, J.J.L.: Self-similar blow-up with a continuous range of values of the aggregated mass for a degenerate Keller–Segel system. Adv. Differ. Equ. 16, 85–112 (2011)
Sugiyama, Y., Yahagi, Y.: Uniqueness and continuity of solution for the initial data in the scaling invariant class of degenerate Keller–Segel system. J. Evol. Equ. 11, 319–337 (2010)
Tello, J.T., Winkler, M.: A chemotaxis system with logistic source. Commun. Partial Differ. Equ. 32, 849–877 (2007)
Wang, R., Wang, T., Zhou, Y.: Blow-up profiles for a semilinear chemotaxis system arising in biology. J. Anal. Appl. 33, 417–428 (2014)
Winkler, M.: Boundedness in the higher-dimensional parabolic–parabolic system with logistic source. Commun. Partial Differ. Equ. 35, 1516–1537 (2010)
Winkler, M.: Aggregation vs. global diffusive behavior in the higher-dimensional Keller–Segel model. J. Differ. Equ. 248, 2889–2905 (2010)
Winkler, M., Djie, K.C.: Boundedness and finite-time collapse in a chemotaxis system with volume-filling effect. Nonlinear Anal. TMA 72, 1044–1064 (2010)
Acknowledgements
This work was supported by the Science and Technology Planning Project of Gansu Province (1610RJZA102), Fundamental Research Funds for the Central Universities (31920170147, 31920180116), and Gansu Provincial First-class Discipline Program of Northwest Minzu University.
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YJ completed the main study and wrote the manuscript, WZ checked the proofs process and verified the calculation. Moreover, all the authors read and approved the last version of the manuscript.
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Jiao, Y., Zeng, W. Blow-up and delay for a parabolic–elliptic Keller–Segel system with a source term. Bound Value Probl 2018, 95 (2018). https://doi.org/10.1186/s13661-018-1013-z
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DOI: https://doi.org/10.1186/s13661-018-1013-z
MSC
- 35K37
- 35B40
- 92D40
Keywords
- Parabolic–elliptic Keller–Segel system
- Blow-up time
- Lower bounds
- Decay